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cathepsin-activated prosense 680 signal  (ProSense Inc)

 
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    Structured Review

    ProSense Inc cathepsin-activated prosense 680 signal
    A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence <t>after</t> <t>ProSense</t> <t>680</t> administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).
    Cathepsin Activated Prosense 680 Signal, supplied by ProSense Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/prosense+680+signal/pmc03956882-218-5-4?v=ProSense+Inc
    Average 90 stars, based on 1 article reviews
    cathepsin-activated prosense 680 signal - by Bioz Stars, 2026-07
    90/100 stars

    Images

    1) Product Images from "Gene Silencing of SOCS3 by siRNA Intranasal Delivery Inhibits Asthma Phenotype in Mice"

    Article Title: Gene Silencing of SOCS3 by siRNA Intranasal Delivery Inhibits Asthma Phenotype in Mice

    Journal: PLoS ONE

    doi: 10.1371/journal.pone.0091996

    A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence after ProSense 680 administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).
    Figure Legend Snippet: A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence after ProSense 680 administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).

    Techniques Used: Micro-CT, In Vivo, Imaging, Fluorescence



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    cathepsin-activated prosense 680 signal  (ProSense Inc)
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    ProSense Inc cathepsin-activated prosense 680 signal
    A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence <t>after</t> <t>ProSense</t> <t>680</t> administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).
    Cathepsin Activated Prosense 680 Signal, supplied by ProSense Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/prosense+680+signal/pmc03956882-218-5-4?v=ProSense+Inc
    Average 90 stars, based on 1 article reviews
    cathepsin-activated prosense 680 signal - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier
    prosense 680 signal  (ProSense Inc)
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    ProSense Inc prosense 680 signal
    A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence <t>after</t> <t>ProSense</t> <t>680</t> administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).
    Prosense 680 Signal, supplied by ProSense Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/prosense+680+signal/pm22751990-102-8-7?v=ProSense+Inc
    Average 90 stars, based on 1 article reviews
    prosense 680 signal - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier
    prosense-680 probe signal  (ProSense Inc)
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    ProSense Inc prosense-680 probe signal
    A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence <t>after</t> <t>ProSense</t> <t>680</t> administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).
    Prosense 680 Probe Signal, supplied by ProSense Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/prosense+680+signal/pm22216767-81-29-29?v=ProSense+Inc
    Average 90 stars, based on 1 article reviews
    prosense-680 probe signal - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier
    prosense-680 signal  (ProSense Inc)
    90
    ProSense Inc prosense-680 signal
    A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence <t>after</t> <t>ProSense</t> <t>680</t> administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).
    Prosense 680 Signal, supplied by ProSense Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/prosense+680+signal/pmc02488397-87-8-8?v=ProSense+Inc
    Average 90 stars, based on 1 article reviews
    prosense-680 signal - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence after ProSense 680 administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).

    Journal: PLoS ONE

    Article Title: Gene Silencing of SOCS3 by siRNA Intranasal Delivery Inhibits Asthma Phenotype in Mice

    doi: 10.1371/journal.pone.0091996

    Figure Lengend Snippet: A . Airway hyperresponsiveness to methacholine challenge. Methacholine dose response curve 24 hours after last OVA administration. Saline group (mean ±SD, n = 13); OVA group (mean ±SD, n = 12); OVA siNT-treated group (mean ±SD, n = 12); and OVA siSOCS3-treated group (mean ±SD, n = 15). B . Native axial micro-CT images of the lungs of typical mice from each experimental group, where hyperintense areas (arrow) correspond to tissue with more fluid than normal. 1: SS n = 4; 2: OVA n = 4; 3: OVA siNT n = 4; 4: OVA siSOCS3 n = 4. * P <0,05 between groups. C . In vivo FMT tomographic imaging. Lung fluorescence after ProSense 680 administration in mice. Three-dimensional regions of interest were placed within the lung region. 1: SS group; 2: OVA group; 3: OVA siNT group; 4: OVA siSOCS3 group. C . 3D FMT quantification of pulmonary inflammation, expressed as total pmoles per lung ± S.D († P <0,01) of ProSense 680 fluorescence within the lung region of each mouse from all the study groups (SS n = 4, OVA n = 4, OVA siNT n = 4, OVA siSOCS3 n = 4).

    Article Snippet: Quantification of the cathepsin-activated ProSense 680 signal provides a noninvasive measure of pulmonary eosinophilia due to specific protease activation of ProSense by eosinophils .

    Techniques: Micro-CT, In Vivo, Imaging, Fluorescence